Pathway Ontology

Last uploaded: November 13, 2023
Preferred Name

breast cancer pathway

Synonyms

breast neoplasm

Definitions

Breast cancer or neoplasm is the most common cancer among women and the second worldwide after lung cancer. Deregulated pathways such estrogen or PI3K-Akt signaling have been implicated in breast cancer. In many cases, the disease is estrogen-dependent and it is possible that dysregulation of miRNA may correlate with the expression of estrogen receptor. Mutations in a number of other genes such as Brca1, 2 and 3 or p53 have also been associated with breast cancer.

ID

http://purl.obolibrary.org/obo/PW_0000624

definition

Breast cancer or neoplasm is the most common cancer among women and the second worldwide after lung cancer. Deregulated pathways such estrogen or PI3K-Akt signaling have been implicated in breast cancer. In many cases, the disease is estrogen-dependent and it is possible that dysregulation of miRNA may correlate with the expression of estrogen receptor. Mutations in a number of other genes such as Brca1, 2 and 3 or p53 have also been associated with breast cancer.

has_obo_namespace

pathway

has_related_synonym

breast neoplasm

id

PW:0000624

label

breast cancer pathway

notation

PW:0000624

prefLabel

breast cancer pathway

treeView

http://purl.obolibrary.org/obo/PW_0000605

subClassOf

http://purl.obolibrary.org/obo/PW_0000605

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http://scai.fraunhofer.de/PWDICT#ID0628 PTS LOOM