SNOMED CT

Last uploaded: January 16, 2025
Id http://purl.bioontology.org/ontology/SNOMEDCT/715737004
http://purl.bioontology.org/ontology/SNOMEDCT/715737004
Preferred Name

Parkinsonism with dementia of Guadeloupe

Definitions
Main features described as symmetrical bradykinesia, predominantly axial rigidity, postural instability with early falls and cognitive decline with prominent features of frontal lobe dysfunction. Prevalence is unknown, but a higher number of cases have been described in the French West Indies. This form of atypical parkinsonism may be related to exposure to tropical plants containing mitochondrial complex I inhibitors. Guadelupian parkinsonism may actually be a tauopathy identical or closely related to progressive supranuclear palsy. Most patients are L-dopa unresponsive.
Synonyms
Parkinsonism co-occurrent with dementia of Guadeloupe
Parkinsonism co-occurrent with dementia of Guadeloupe (disorder)
Type http://www.w3.org/2002/07/owl#Class
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