Preferred Name

Debrisoquin [Chemical/Ingredient]

Synonyms

2(1H)-Isoquinolinecarboximidamide, 3,4-dihydro-

ID

http://purl.bioontology.org/ontology/NDFRT/N0000166976

altLabel

2(1H)-Isoquinolinecarboximidamide, 3,4-dihydro-

Debrisoquine

Debrisoquin

cui

C0011082

MESH DEFINITION

An adrenergic neuron-blocking drug similar in effects to GUANETHIDINE. It is also noteworthy in being a substrate for a polymorphic cytochrome P-450 enzyme. Persons with certain isoforms of this enzyme are unable to properly metabolize this and many other clinically important drugs. They are commonly referred to as having a debrisoquin 4-hydroxylase polymorphism.

MESH DUI

D003647

MeSH name

Debrisoquin

MESH UI

M0005709

NDFRT kind

INGREDIENT_KIND

notation

N0000166976

NUI

N0000166976

prefLabel

Debrisoquin [Chemical/Ingredient]

tui

T109

T121

subClassOf

http://purl.bioontology.org/ontology/NDFRT/N0000007960

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