Preferred Name |
Debrisoquin [Chemical/Ingredient] |
|
Synonyms |
2(1H)-Isoquinolinecarboximidamide, 3,4-dihydro- |
|
ID |
http://purl.bioontology.org/ontology/NDFRT/N0000166976 |
|
altLabel |
2(1H)-Isoquinolinecarboximidamide, 3,4-dihydro- Debrisoquine Debrisoquin |
|
cui |
C0011082 |
|
MESH DEFINITION |
An adrenergic neuron-blocking drug similar in effects to GUANETHIDINE. It is also noteworthy in being a substrate for a polymorphic cytochrome P-450 enzyme. Persons with certain isoforms of this enzyme are unable to properly metabolize this and many other clinically important drugs. They are commonly referred to as having a debrisoquin 4-hydroxylase polymorphism. |
|
MESH DUI |
D003647 |
|
MeSH name |
Debrisoquin |
|
MESH UI |
M0005709 |
|
NDFRT kind |
INGREDIENT_KIND |
|
notation |
N0000166976 |
|
NUI |
N0000166976 |
|
prefLabel |
Debrisoquin [Chemical/Ingredient] |
|
tui |
T109 T121 |
|
subClassOf |
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