Pathway Ontology

Last uploaded: October 21, 2024
Id http://purl.obolibrary.org/obo/PW_0001515
http://purl.obolibrary.org/obo/PW_0001515
Preferred Name

Hippo signaling pathway

Definitions
The Hippo signaling pathway plays important roles in organ development and growth and tumor suppression. The pathway consists of a core of four kinases which once activated by upstream regulators promote the cytoplasmic sequestration of YAP/TAZ transcriptional regulators. Dysregulation of the pathway has been implicated in tumor metastasis.
Synonyms
Signaling by Hippo
hippo signaling
Type http://www.w3.org/2002/07/owl#Class
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