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Physician Data Query
Id | http://purl.bioontology.org/ontology/PDQ/CDR0000039106
http://purl.bioontology.org/ontology/PDQ/CDR0000039106
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Preferred Name | itraconazole |
Definitions |
A synthetic triazole agent with antimycotic properties. Formulated for both topical and systemic use, itraconazole preferentially inhibits fugal cytochrome P450 enzymes, resulting in a decrease in fungal ergosterol synthesis. Because of its low toxicity profile, this agent can be used for long-term maintenance treatment of chronic fungal infections. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C1138" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C1138" NCI Thesaurus)
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Synonyms |
Sporanox
ICZ
Lozanoc
R 51,211
oriconazole
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Type | http://www.w3.org/2002/07/owl#Class |
All Properties
definition | A synthetic triazole agent with antimycotic properties. Formulated for both topical and systemic use, itraconazole preferentially inhibits fugal cytochrome P450 enzymes, resulting in a decrease in fungal ergosterol synthesis. Because of its low toxicity profile, this agent can be used for long-term maintenance treatment of chronic fungal infections. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C1138" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C1138" NCI Thesaurus) |
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altLabel |
Sporanox
ICZ
Lozanoc
R 51,211
oriconazole
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prefLabel | itraconazole
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CAS Registry | 84625-61-6
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notation | CDR0000039106
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ORIG STY | Drug/agent
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Component of | |
Legacy PDQ ID | 1698
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Date last modified | 2016-03-23
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Semantic type UMLS property | |
NCI ID | C1138
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type | |
LT | TRD
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tui |
T109
T121
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cui |
C0729171
C0699614
C4087049
C0064113
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