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Physician Data Query
Acronym | PDQ |
Visibility | Public |
Description | Physician Data Query (PDQ) Terminology is part of NCI's comprehensive cancer information database, which contains expert summaries on a wide range of cancer topics, a listing of some 30,000 cancer clinical trials from around the world, a directory of genetics services professionals, the NCI Dictionary of Cancer Terms, and the NCI Drug Dictionary. |
Status | Production |
Format | UMLS |
Contact | Volker Englisch, volker@mail.nih.gov |
Categories | Health |
Groups | Unified Medical Language System |
License Information | This ontology is made available via the UMLS. Users of all UMLS ontologies must abide by the terms of the UMLS license. |
Version | Released | Uploaded | Downloads |
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PDQ_2018_10_27 (Parsed, Indexed, Metrics, Annotator) | 05/06/2019 | 08/27/2019 | RDF/TTL | CSV | Diff |
2018AB (Archived) | 11/05/2018 | 04/29/2019 | RDF/TTL | Diff |
2018AA (Archived) | 05/07/2018 | 07/06/2018 | RDF/TTL | Diff |
2017AB (Archived) | 11/06/2017 | 07/06/2018 | RDF/TTL | Diff |
2017AA (Archived) | 05/08/2017 | 04/06/2018 | RDF/TTL | Diff |
2016AB (Archived) | 02/06/2017 | 02/06/2017 | RDF/TTL | Diff |
2016AA (Archived) | 09/06/2016 | 09/06/2016 | RDF/TTL | Diff |
2015AB (Archived) | 07/20/2016 | 07/20/2016 | RDF/TTL | Diff |
2015AA (Archived) | 06/09/2015 | 06/09/2015 | RDF/TTL | Diff |
2014AB (Archived) | 01/29/2015 | 01/29/2015 | RDF/TTL | Diff |
2014AA (Archived) | 05/28/2014 | 05/28/2014 | RDF/TTL | Diff |
2013AB (Archived) | 02/18/2014 | 02/18/2014 | RDF/TTL | Diff |
2013AA (Archived) | 01/14/2014 | 01/14/2014 | RDF/TTL | Diff |
2013AA (Archived) | 05/08/2013 | 09/25/2013 | RDF/TTL | Diff |
2010_04_09 (Archived) | 04/09/2010 | 11/18/2010 | RDF/TTL |
2007_02 (Archived) | 02/01/2007 | 07/31/2009 | RDF/TTL |
more... |
No views of PDQ available
Id | http://purl.bioontology.org/ontology/PDQ/CDR0000039484
http://purl.bioontology.org/ontology/PDQ/CDR0000039484
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Preferred Name | isoniazid |
Definitions |
A synthetic derivative of nicotinic acid with anti-mycobacterial properties. Although its mechanism of action is still unclear, isoniazid appears to block the synthesis of mycolic acids, major components of the mycobacterial cell wall. This agent is only active against actively growing mycobacteria because, as a pro-drug, it requires activation in susceptible mycobacterial species. Isoniazid also interferes with mycobacterial metabolism of vitamin B6. Resistance occurs due to decreased bacterial wall penetration. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C600" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C600" NCI Thesaurus)
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Synonyms |
isonicotinic acid hydrazide
INH
isonicotinyl hydrazine
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Type | http://www.w3.org/2002/07/owl#Class |
All Properties
definition | A synthetic derivative of nicotinic acid with anti-mycobacterial properties. Although its mechanism of action is still unclear, isoniazid appears to block the synthesis of mycolic acids, major components of the mycobacterial cell wall. This agent is only active against actively growing mycobacteria because, as a pro-drug, it requires activation in susceptible mycobacterial species. Isoniazid also interferes with mycobacterial metabolism of vitamin B6. Resistance occurs due to decreased bacterial wall penetration. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C600" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C600" NCI Thesaurus) |
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altLabel |
isonicotinic acid hydrazide
INH
isonicotinyl hydrazine
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prefLabel | isoniazid
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CAS Registry | 54-85-3
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notation | CDR0000039484
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NSC Code | 9659
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ORIG STY | Drug/agent
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Component of | |
Legacy PDQ ID | 2118
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Date last modified | 2006-12-14
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Semantic type UMLS property | |
NCI ID | C600
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type | |
tui |
T109
T121
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cui | C0022209
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