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Physician Data Query
Acronym | PDQ |
Visibility | Public |
Description | Physician Data Query (PDQ) Terminology is part of NCI's comprehensive cancer information database, which contains expert summaries on a wide range of cancer topics, a listing of some 30,000 cancer clinical trials from around the world, a directory of genetics services professionals, the NCI Dictionary of Cancer Terms, and the NCI Drug Dictionary. |
Status | Production |
Format | UMLS |
Contact | Volker Englisch, volker@mail.nih.gov |
Categories | Health |
Groups | Unified Medical Language System |
License Information | This ontology is made available via the UMLS. Users of all UMLS ontologies must abide by the terms of the UMLS license. |
Version | Released | Uploaded | Downloads |
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PDQ_2018_10_27 (Parsed, Indexed, Metrics, Annotator) | 05/06/2019 | 08/27/2019 | RDF/TTL | CSV | Diff |
2018AB (Archived) | 11/05/2018 | 04/29/2019 | RDF/TTL | Diff |
2018AA (Archived) | 05/07/2018 | 07/06/2018 | RDF/TTL | Diff |
2017AB (Archived) | 11/06/2017 | 07/06/2018 | RDF/TTL | Diff |
2017AA (Archived) | 05/08/2017 | 04/06/2018 | RDF/TTL | Diff |
2016AB (Archived) | 02/06/2017 | 02/06/2017 | RDF/TTL | Diff |
2016AA (Archived) | 09/06/2016 | 09/06/2016 | RDF/TTL | Diff |
2015AB (Archived) | 07/20/2016 | 07/20/2016 | RDF/TTL | Diff |
2015AA (Archived) | 06/09/2015 | 06/09/2015 | RDF/TTL | Diff |
2014AB (Archived) | 01/29/2015 | 01/29/2015 | RDF/TTL | Diff |
2014AA (Archived) | 05/28/2014 | 05/28/2014 | RDF/TTL | Diff |
2013AB (Archived) | 02/18/2014 | 02/18/2014 | RDF/TTL | Diff |
2013AA (Archived) | 01/14/2014 | 01/14/2014 | RDF/TTL | Diff |
2013AA (Archived) | 05/08/2013 | 09/25/2013 | RDF/TTL | Diff |
2010_04_09 (Archived) | 04/09/2010 | 11/18/2010 | RDF/TTL |
2007_02 (Archived) | 02/01/2007 | 07/31/2009 | RDF/TTL |
more... |
No views of PDQ available
Id | http://purl.bioontology.org/ontology/PDQ/CDR0000043417
http://purl.bioontology.org/ontology/PDQ/CDR0000043417
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Preferred Name | cephalexin |
Definitions |
A beta-lactam, first-generation cephalosporin antibiotic with bactericidal activity. Cephalexin binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linking of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis. Compared to second and third generation cephalosporins, cephalexin is more active against gram-positive and less active against gram-negative organisms. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C356" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C356" NCI Thesaurus)
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Synonyms |
Keflex
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Type | http://www.w3.org/2002/07/owl#Class |
All Properties
definition | A beta-lactam, first-generation cephalosporin antibiotic with bactericidal activity. Cephalexin binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linking of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis. Compared to second and third generation cephalosporins, cephalexin is more active against gram-positive and less active against gram-negative organisms. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C356" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C356" NCI Thesaurus) |
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altLabel | Keflex
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prefLabel | cephalexin
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CAS Registry | 15686-71-2
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notation | CDR0000043417
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ORIG STY | Drug/agent
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Legacy PDQ ID | 7976
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Semantic type UMLS property | |
NCI ID | C356
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type | |
LT | TRD
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tui |
T109
T195
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cui |
C0700517
C0007716
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