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Physician Data Query
Id | http://purl.bioontology.org/ontology/PDQ/CDR0000649799
http://purl.bioontology.org/ontology/PDQ/CDR0000649799
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Preferred Name | triamcinolone acetonide |
Definitions |
The acetonide salt of triamcinolone, a synthetic glucocorticosteroid with immunosuppressive and anti-inflammatory activities. Triamcinolone binds to specific cytosolic glucocorticoid receptors, which subsequently interact with the glucocorticoid receptor response element on DNA, gene expression is altered so that the synthesis of certain anti-inflammatory proteins is induced while the synthesis of certain inflammatory mediators is inhibited. Consequently, chronic inflammatory and autoimmune reactions are reduced. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C48027" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C48027" NCI Thesaurus)
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Synonyms |
AllerNaze
9-alpha-fluoro-11-beta,21-dihydroxy-16-alpha-isopropylidenedioxy-1,4-pregnadiene,3,20-dione
Nasacort
Kenalog
Aristocort A
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Type | http://www.w3.org/2002/07/owl#Class |
All Properties
definition | The acetonide salt of triamcinolone, a synthetic glucocorticosteroid with immunosuppressive and anti-inflammatory activities. Triamcinolone binds to specific cytosolic glucocorticoid receptors, which subsequently interact with the glucocorticoid receptor response element on DNA, gene expression is altered so that the synthesis of certain anti-inflammatory proteins is induced while the synthesis of certain inflammatory mediators is inhibited. Consequently, chronic inflammatory and autoimmune reactions are reduced. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C48027" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C48027" NCI Thesaurus) |
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altLabel |
AllerNaze
9-alpha-fluoro-11-beta,21-dihydroxy-16-alpha-isopropylidenedioxy-1,4-pregnadiene,3,20-dione
Nasacort
Kenalog
Aristocort A
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prefLabel | triamcinolone acetonide
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CAS Registry | 76-25-5
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notation | CDR0000649799
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NSC Code | 21916
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ORIG STY | Drug/agent
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Date last modified | 2009-07-14
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Semantic type UMLS property | |
NCI ID | C48027
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type | |
LT | TRD
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tui |
T109
T121
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DATE FIRST PUBLISHED | 2009-07-14
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cui |
C2608734
C0699689
C0040866
C0718648
C0594040
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