Physician Data Query

Last uploaded: August 27, 2019
Id http://purl.bioontology.org/ontology/PDQ/CDR0000761171
http://purl.bioontology.org/ontology/PDQ/CDR0000761171
Preferred Name

chlorogenic acid

Definitions
A polyphenol and the ester of caffeic acid and quinic acid that is found in coffee and black tea, with potential antioxidant and chemopreventive activities. Chlorogenic acid scavenges free radicals, which inhibits DNA damage and may protect against the induction of carcinogenesis. In addition, this agent may upregulate the expression of genes involved in the activation of the immune system and enhance activation and proliferation of cytotoxic T-lymphocytes, macrophages, and natural killer cells. Chlorogenic acid also inhibits the activity of matrix metalloproteinases. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C116073" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C116073" NCI Thesaurus)
Synonyms
5-O-(3,4-dihydroxycinnamoyl)-L-quinic acid
3-caffeoylquinic acid
Type http://www.w3.org/2002/07/owl#Class
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